Visceral adiposity index correlation with Rotterdam criteria in patients with polycystic ovary syndrome

Background: The present research explores the correlation of visceral obesity index with Rotterdam criteria (hyperandrogenism and/or hyperandrogenemia, oligomenorrhea and Ultrasound polycystic ovarian morphology) among Egyptian polycystic ovary syndrome patients. Methods: We enrolled one hundred female patients with polycystic ovary syndrome with age ranged 18-44 years (mean age 26.83±6.092 years). Results: VAI very strongly correlated with waist circumference, TG and HDL-c, also moderately correlated with systolic B.P, BMI, HOMA-IR and insulin levels, also we found only insulin, menstrual cycles per year number and FGS were significant predictors of hyperandrogenemia in PCOS patients. Only Ultrasound polycystic ovarian morphology was a significant risk factor for oligomenorrhea in PCOS patients in logistic regression analysis. VAI, TT and Farman gallawy score can significantly predict number of the menstrual cycles per year number (p <0.05). In logistic regression analysis, only oligomenorrhea was a significant independent risk factor for PCOM (p <0.05). In addition, only VAI was a significant independent (p <0.05) risk factor for metabolic syndrome. Conclusions: VAI was an independent significant predictor for metabolic syndrome in patients with PCOS and a good marker of cardiometabolic risk in PCOS patients. In addition, VAI was significant predictors of annual menusteral cycle but not testosterone levels or polycystic ovarian morphology in PCOS. This study confirms the value of VAI in identification of patient with risk for metabolic syndrome and cardiometabolic risk in PCOS patients, but not found a role for VAI in diagnosis of PCOS.